Kawasaki Disease Complicated by Peripheral Gangrene in a Case of Inherited Thrombophilia

Abstract

Kawasaki disease is a febrile vasculitis targeting medium sized arteries, causing coronary artery aneurysm without appropriate treatment. Many children do not fulfill the criteria and due to its serious complications, the American Heart Association (AHA) published an algorithm for atypical Kawasaki disease based on laboratory tests and echocardiography. Peripheral ischemia is a rare complication with harmful sequalae. Here we reports a case of a 14-month-old patient, who was diagnosed of atypical Kawasaki disease, developed peripheral ischemia and gangrene of the second and third right hand fingers, and was found to have factor V Leiden heterozygous mutation.




Int J Clin Pediatr. 2018;7(3):43-45
doi: https://doi.org/10.14740/ijcp306w