International Journal of Clinical Pediatrics


Itzhak Brook, MD, MSc, Professor of Pediatrics and Medicine at Georgetown University School of Medicine, Washington DC, USA. More...

ISSN 1927-1255 print  |  ISSN 1927-1263 online  |  Quarterly  |  Open Access  |  Aims and Scope

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Combat the COVID-19

Let's Combat COVID-19 Pandemic Together
The COVID-19 outbreak presents the unprecedented challenge for world public and medical practitioners and health care providers. The Elmer Press Inc is herein to participate the combating COVID-19 through all possible efforts, as a clinical medicine publisher, we would facilitate the rapid and effective communication of management of this pandemic, we will consider submissions related to all aspects of this disease, including prevention, basic viral research, epidemiology, treatment, vaccine, fast screening, diagnosis, prognosis, etc. We will process such manuscripts in priority and publish them ASAP after peer-reviewed and accepted.



  • Elevated Lipase Associated With COVID-19 Possibly due to Acute Pancreatitis in a Pediatric Patient: A Case Report

    As the global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) advances, the challenge of understanding its wide spectrum of symptoms and sequelae continues to be a priority in the medical world. There are not many case reports on the atypical presenting features of coronavirus disease 2019 (COVID-19), especially in the pediatric population.

  • Impact of Oxygen Delivery Patterns on Arterial Oxygen Saturation Among Children

    Adequate oxygenation to treat hypoxia by suitable oxygen delivery pattern is the essence of pediatric critical care medicine. Monitoring oxygen saturation (SpO2) is thus essential in order to decide course of treatment.

  • Arm Swelling From Subclavian Vein Thrombosis: Factor V Leiden Mutation

    Factor V Leiden is a genetic condition that can decrease natural anticoagulant effect in response to activated protein C, increasing thromboembolic risk. We report a 17-year-old man, homozygous for the Factor V Leiden mutation, with sudden onset arm stiffness, pain and swelling caused by a deep vein thrombosis in the subclavian vein.

  • Risks Associated With Conventional Humidifiers Adapted for High-Flow Nasal Cannula Therapy in Human Infants: Results of a Time and Motion Study

    High-flow nasal cannula (HFNC) therapy was introduced into neonatology with novel heating-humidification technology; however, the therapy is currently being applied with adapted conventional humidifiers.

  • Vascular Ring in an Infant With Cystic Fibrosis

    A vascular ring (VR) is a rare congenital anomaly that has variable clinical presentation, but may cause trachea-esophageal compressive symptoms.





Image of the Issue


Management of Severe COVID-19 Infection in Children: A Therapeutic Challenge

Although coronavirus disease 2019 (COVID-19) occurs in children, compared to adults they have a milder disease. They are infrequently admitted to intensive care units, have better prognosis and their mortality is low. However, because children are often asymptomatic or experience a mild disease the true incidence of COVID-19 in children may be higher. Full Text

COVID-19 in a Down Syndrome Newborn
A 36-week premature newborn with trisomy 21, had a fever, runny nose and mild dyspnea at 27 days old. Parents had flu-like symptoms. He was admitted to intensive care unit (ICU), in isolation with support therapy. His reverse transcription-polymerase chain reaction (RT-PCR) test for coronavirus disease 2019 (COVID-19) was positive.
Full Text

Featured Article


Prognostic Significance of P16, EZH2, FOXJ1, and Tenascin Expression in Pediatric Ependymoma
The prognosis of pediatric ependymomas remains poor, with treatment being predominantly based on surgery with or without radiotherapy. The lack of robust therapeutic molecular markers for clinical use has hampered attempts to improve survival from ependymomas. This study aimed to assess the prognostic significance of p16, enhancer of zeste homolog 2 (EZH2), forkhead box protein J 1 (FOXJ1), and tenascin in pediatric ependymomas by evaluating their immunohistochemical expression and comparing them with clinical outcomes. Full Text

Current Issue

Vol. 9, No. 4, Dec 2020

Table of Contents


Management of Severe COVID-19 Infection in Children: A Therapeutic Challenge Abstract HTML PDF
Itzhak Brook 103-104

Original Article

Work Engagement as a Measure of Wellness in Pediatric Hospital Medicine Abstract HTML PDF Suppl1
Elise P. Lu, Kathryn Leyens, Tony Tarchichi, Sylvia Choi, Sara McIntire, Andrew McCormick 105-109

Case Report

Perineal Groove in a Neonate With Increased Maternal Serum Alpha-Fetoprotein Abstract HTML PDF
Jameson M. Petrochko, Jennifer A. Canning, Chaminie A. Wheeler 110-115
COVID-19 in a Down Syndrome Newborn Abstract HTML PDF
Gabriela Caroline Lobato Pontes, Ariella Cristina Rego Lobato, Samela Miranda da Silva, Daniel Figueiredo Alves da Silva, Alexandre Ferreira da Silva, Rodrigo Santiago Barbosa Rocha, Bianca Duarte de Oliveira, Tallita Olga Calvinho Martins, Aurimery Gomes Chermont, Katiane da Costa Cunha 116-119
Non-Cardiogenic Pulmonary Edema With Refractory Hypotension in a Child From Amlodipine Overdoses Abstract HTML PDF
Inva Gjeta, Durim Sala, Iliriana Bakalli, Ermela Celaj, Elmira Kola 120-124
Elevated Lipase Associated With COVID-19 Possibly due to Acute Pancreatitis in a Pediatric Patient: A Case Report Abstract HTML PDF
Shruthi Shekar, Neelam Sarwar, Mudit Kalia, Joseph Castellanos, Frances Pelliccia, Jagdip Gill 125-129
Insights Into Management of Camurati-Engelmann Disease: A Case Series of Three Siblings Abstract HTML PDF
W. Hunter Slemp, Janel D. Hunter, Elizabeth T. Walsh, Cathrine Constantacos, David F. Crudo 130-134
Febrile Morbilliform Rash as a Clinical Presentation of COVID-19 in a Pediatric Patient Abstract HTML PDF
Muneer Almutairi, Amani Azizalrahman 135-137

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International Journal of Clinical Pediatrics






International Journal of Clinical Pediatrics, quarterly, ISSN 1927-1255 (print), 1927-1263 (online), published by Elmer Press Inc.             
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