Lane-Hamilton Syndrome With Respiratory Failure: A Case Report

Abstract

Lane-Hamilton syndrome is a rare coexistence of idiopathic pulmonary hemosiderosis with celiac disease. Idiopathic pulmonary hemorrhage presents clinically as a classic triad of hemoptysis, iron deficiency anemia and infiltrates on chest radiograph with a variable clinical course. Celiac disease is an autoimmune enteropathy in genetically susceptible individuals triggered by gluten-containing food. We describe a 12-year-old girl with Lane-Hamilton syndrome presenting with severe anemia, pulmonary hemorrhage and respiratory failure. The child had remained previously asymptomatic. A high index of suspicion is required for diagnosis of Lane-Hamilton syndrome in a critically ill child.

Int J Clin Pediatr. 2020;9(3):87-91
doi: https://doi.org/10.14740/ijcp379