Arm Swelling From Subclavian Vein Thrombosis: Factor V Leiden Mutation

Shawn X. Wen, Katherine N. Tom, Yousef Etoom, Jonathan P. Wong, Rosemary G. Moodie, Ibrahim Al-Hashmi, Leonardo R. Brandao, Peter D. Wong

Abstract


Factor V Leiden is a genetic condition that can decrease natural anticoagulant effect in response to activated protein C, increasing thromboembolic risk. We report a 17-year-old man, homozygous for the Factor V Leiden mutation, with sudden onset arm stiffness, pain and swelling caused by a deep vein thrombosis in the subclavian vein. Pediatricians should consider thromboembolic diseases in cases of spontaneous acute limb discomfort and discoloration with no obvious cause.




Int J Clin Pediatr. 2020;9(1):1-3
doi: https://doi.org/10.14740/ijcp343

Keywords


Thromboembolic disease; Factor V Leiden; Deep venous thrombosis

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