International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access |
Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc |
Journal website http://www.theijcp.org |
Original Article
Volume 1, Number 4-5, October 2012, pages 103-108
Clinical, Laboratory, and Ultrasound Characteristics of Knee Involvement in Children With Juvenile Rheumatoid Arthritis
Figure
Tables
Variable | Data |
---|---|
Disease duration (months) mean ± SD (range) | 53.3 ± 17.5 (4 - 103) |
JRA subtype | |
- polyarticular | 8/19 (42.1%) |
- oligoarticular | 8/19 (42.1%) |
- systemic | 3/19 (15.8%) |
Active knee joint patients’ n (%) | 12/19 (63.1%) |
Bilateral clinical knee involvement n (%) | 5 (26.3%) |
Ritchie articular index score, mean ± SD | 15.2 ± 9.6 |
Steinbrocker grading system, mean ± SD (grade 0 - 4) | 2 ± 1.2 |
Childhood Health Assessment Questionnaire (CHAQ), mean ± SD | 1.2 ± 1.1 |
Visual analog scale (0 - 10 cm), mean ± SD | 3.8 ± 2.4 |
Variable | Patients with active knee | Patients with inactive knee | P value | |
---|---|---|---|---|
N = 12 | N = 7 | |||
n = number, ESR = erythrocyte sedimentation rate, CRP= C-reactive protein, ANA = antinuclear antibody, USG = ultrsonography. | ||||
Clinical | (1) Ritchie articular index score, mean ± SD | 19.5 ± 5.8 | 10.1 ± 4.5 | 0.0014 |
(2) Steinbrocker grading system, mean ± SD | 3.2 ± 1.2 | 1.1 ± 0.7 | 0.0002 | |
(3) Childhood Health Assessment Questionnaire (CHAQ), mean ± SD | 2.2 ± 1.2 | 1.1 ± 0.4 | 0.0155 | |
(4) Visual analog scale (0 - 10 cm), mean ± SD | 6.8 ± 3.2 | 2.7 ± 1.4 | 0.002 | |
Laboratory | (1) Complete blood count (CBC) | |||
- Hemoglobin (g/dL), mean ± SD | 9.4 ± 2.7 | 12.6 ± 2.4 | 0.0208 | |
- Leucocytosis (n positive) (%) | 5/12(41.7%) | 1/7(14.3%) | 0.2155 | |
- Thrombocytosis (n positive) (%) | 6/12(50%) | 2/7 (28.6%) | 0.3614 | |
(2) ESR (mm/hour), mean ± SD | 54.5 ± 18.9 | 24.3 ± 14.8 | 0.0015 | |
(3) CRP level (mg/L), mean ± SD | 22.7 ± 11.4 | 12.6 ± 4 | 0.0117 | |
(4) Rheumatoid factor (n positive) (%) | 5/12(41.7%) | 2/7 (28.6%) | 0.5681 | |
(5) ANA (n positive) (%) | 2/12 (16.7% ) | 2/7 (28.6%) | 0.5392 | |
Ultra-sonographic | (1) USG knee synovial thickness (mm), mean ± SD | 3.2 ± 1.8 | 1.1 ± 0.9 | 0.0047 |
(2) USG knee effusion volume (mL), mean ± SD | 4.3 ± 2.4 | 2.1 ± 0.9 | 0.0141 |