Figure 1. A flowchart of study procedure including patients’ enrollment, allocation, follow up and analysis.
| International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc |
| Journal website http://www.theijcp.org |
Original Article
Volume 1, Number 2-3, June 2012, pages 76-81
Clinical, Laboratory and Radiological Predictors of Extension of Oligoarticular Juvenile Idiopathic Arthritis: A Prospective Study
Figure
Tables
| Persistent oligoarticular JIA group (N=28) | Extended oligoarticular JIA group (N=12) | p-value | |
|---|---|---|---|
| Abbreviations: CHAQ, Childhood Health Assessment Questionnaire (CHAQ) | |||
| Age: (years) | 0.001 | ||
| - Mean ± SD | 7.4 ± 3.1 | 10.4 ± 2.1 | |
| - Range | 4.1 - 10.9 | 5.3 - 12.5 | |
| Gender | 0.763 | ||
| - Male | 20/28 (71.4%) | 8/12 (66.6%) | |
| - Female (female %) | 8/28 (28.6%) | 4/12 (33.3%) | |
| Disease duration (months) | 0.445 | ||
| - Mean ± SD | 15.7 ± 7.2 | 17.7 ± 6.3 | |
| - Range | 6.3 - 23.4 | 6.9 - 23.7 | |
| Joint involvement (No & %) | |||
| - Upper limbs | 3/28 (10.7%) | 10/12 (83.3%) | < 0.0001 |
| - Lower limbs | 26/28 (92.8%) | 6/12 (50%) | 0.002 |
| - Bilateral symmetrical | 4/28 (14.3%) | 7/12 (58.3) | 0.004 |
| Functional capacity grade (0 - 4) (Mean ± SD) | 1.3 ± 1.1 | 2.6 ± 1.5 | 0.019 |
| Ritchie articular index (Mean ± SD) | 14.6 ± 6.4 | 28.3 ± 10.6 | 0.0009 |
| Visual analog scale (cm) (Mean ± SD) | 4.9 ± 2.2 | 7.8 ± 3.8 | 0.022 |
| CHAQ, (Mean ± SD) | 1.07 ± 1.1 | 1.9 ± 1.2 | 0.042 |
| Iridocyclitis (No & %) | 1/28 (3.6%) | 0/12 (0%) | 0.507 |
| Persistent oligoarticular JIA group (N = 28) | Extended oligoarticular JIA group (N = 12) | p-value | |
|---|---|---|---|
| Abbreviations: ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; ANA, antineuclear antibody; JAO, juxtaarticular osteoprosis | |||
| ESR level (mm/hour), (Mean ± SD) | 33.9 ± 12.1 | 55.6 ± 19.7 | 0.003 |
| CRP level (mg/L), (Mean ± SD) | 9.1 ± 4.5 | 22.3 ± 10.6 | 0.001 |
| Rheumatoid factor positivity (No & %) | 0/28 (0%) | 7/12 (58.3) | < 0.0001 |
| Anemia (Hb < 11gm %) (No & %) | 12/28(42.9%) | 4/12 (33.3%) | 0.573 |
| ANA positivity (No & %) | 12/28(42.9%) | 1/12 (8.3%) | 0. 033 |
| Radiological changes mainly JAO (No & %) | 5/28 (17.9%) | 6/12 (50%) | 0. 037 |