Int J Clin Pediatr

International Journal of Clinical Pediatrics, ISSN 1927-1255 print, 1927-1263 online, Open Access

Article copyright, the authors; Journal compilation copyright, Int J Clin Pediatr and Elmer Press Inc

Journal website http://www.theijcp.org

Original Article

Volume 3, Number 1, March 2014, pages 5-11

Biochemical Profiling Study in Umbilical Cord Blood as Predictors of Neonatal Damage

**Table 1.** Maternal Age and Gestation Weeks, Newborn Weight and Biochemical Parameters in Maternal Venous Blood and Umbilical Cord Blood in Control and Pathological Groups Expressed as the Mean and Their Respective Standard Deviation Values
	Maternal venous blood	Umbilical cord blood
ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; CK: creatine kinase; LDH: lactate dehydrogenase; hsCRP: high sensitivity C-reactive protein. *Statistically significant difference; ns: non-significant difference.
Mothers age (years)	27 ± 7	28 ± 8	ns
Gestation weeks	38.8 ± 1.5	37.1 ± 2.8	< 0.001*
Newborn weight (g)				3,394 ± 371	2,936 ± 784	< 0.001*
Glucose (mg/dL)	77 ± 29	81 ± 52	ns	58 ± 29	55 ± 31	ns
Urea (mg/dL)	22 ± 7	22 ± 9	ns	20 ± 5	20 ± 6	ns
Cholesterol (mg/dL)	236 ± 54	230 ± 58	ns	68 ± 27	74 ± 33	0.01*
Triglycerides (mg/dL)	208 ± 71	218 ± 102	ns	32 ± 13	37 ± 48	< 0.001*
Uric acid (mg/dL)	4.5 ± 1.2	4.7 ± 1.3	0.04*	4.4 ± 1.2	4.7 ± 1.4	0.03*
Creatinine (mg/dL)	0.6 ± 0.1	0.6 ± 0.4	ns	0.5 ± 0.2	0.5 ± 0.2	ns
Calcium (mg/dL)	8.7 ± 0.6	8.7 ± 0.7	ns	10.0 ± 1.3	10.1 ± 1.0	ns
Phosphorus (mg/dL)	4.1 ± 1.2	4.2 ± 1.3	ns	6.1 ± 2.1	6.3 ± 2.2	ns
Magnesium (mg/dL)	1.8 ± 0.2	1.8 ± 0.2	ns	1.9 ± 0.3	2.0 ± 0.4	ns
Sodium (mEq/L)	138 ± 13	140 ± 5	ns	138 ± 8	139 ± 8	ns
Potassium (mEq/L)	4.3 ± 0.6	4.4 ± 1.4	ns	5.7 ± 1.3	6.3 ± 1.8	< 0.001*
Chlorine (mEq/L)	106 ± 5	106 ± 5	ns	105 ± 7	106 ± 7	ns
Iron (µg/dL)	66 ± 47	65 ± 49	ns	151 ± 38	146 ± 49	ns
Total bilirubin (mg/dL)	0.3 ± 0.2	0.3 ± 0.2	ns	1.5 ± 0.9	1.7 ± 1.3	0.04*
ALT (IU/L)	11 ± 8	18 ± 41	0.02*	8 ± 4	8 ± 6	ns
AST (IU/L)	24 ± 8	29 ± 35	0.04*	35 ± 11	38 ± 20	< 0.001*
ALP (IU/L)	304 ± 160	315 ± 190	ns	337 ± 208	328 ± 181	ns
LDH (IU/L)	443 ± 133	452 ± 136	ns	804 ± 353	848 ± 336	ns
CK (IU/L)	229 ± 174	198 ± 203	ns	312 ± 190	275 ± 121	< 0.001*
GGT (IU/L)	12 ± 7	20 ± 26	< 0.001*	96 ± 56	118 ± 77	< 0.001*
hsCRP (mg(L)	53 ± 67	59 ± 68	ns	0.4 ± 0.8	0.2 ± 0.3	ns
Albumin (g/dL)	3.2 ± 0.5	3.1 ± 0.3	ns	3.8 ± 0.3	3.6 ± 0.5	< 0.001*
Protein (g/dL)	5.8 ± 0.7	5.8 ± 0.6	ns	5.6 ± 0.6	5.3 ± 0.8	< 0.001*

Table 1. Maternal Age and Gestation Weeks, Newborn Weight and Biochemical Parameters in Maternal Venous Blood and Umbilical Cord Blood in Control and Pathological Groups Expressed as the Mean and Their Respective Standard Deviation Values

Maternal venous blood

Umbilical cord blood

Controls (99)

Pathological (184)

Controls (99)

Pathological (184)

ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; CK: creatine kinase; LDH: lactate dehydrogenase; hsCRP: high sensitivity C-reactive protein. *Statistically significant difference; ns: non-significant difference.

Mothers age (years)

27 ± 7

28 ± 8

Gestation weeks

38.8 ± 1.5

37.1 ± 2.8

< 0.001*

Newborn weight (g)

3,394 ± 371

2,936 ± 784

< 0.001*

Glucose (mg/dL)

77 ± 29

81 ± 52

58 ± 29

55 ± 31

Urea (mg/dL)

22 ± 7

22 ± 9

20 ± 5

20 ± 6

Cholesterol (mg/dL)

236 ± 54

230 ± 58

68 ± 27

74 ± 33

0.01*

Triglycerides (mg/dL)

208 ± 71

218 ± 102

32 ± 13

37 ± 48

< 0.001*

Uric acid (mg/dL)

4.5 ± 1.2

4.7 ± 1.3

0.04*

4.4 ± 1.2

4.7 ± 1.4

0.03*

Creatinine (mg/dL)

0.6 ± 0.1

0.6 ± 0.4

0.5 ± 0.2

Calcium (mg/dL)

8.7 ± 0.6

8.7 ± 0.7

10.0 ± 1.3

10.1 ± 1.0

Phosphorus (mg/dL)

4.1 ± 1.2

4.2 ± 1.3

6.1 ± 2.1

6.3 ± 2.2

Magnesium (mg/dL)

1.8 ± 0.2

1.9 ± 0.3

2.0 ± 0.4

Sodium (mEq/L)

138 ± 13

140 ± 5

138 ± 8

139 ± 8

Potassium (mEq/L)

4.3 ± 0.6

4.4 ± 1.4

5.7 ± 1.3

6.3 ± 1.8

< 0.001*

Chlorine (mEq/L)

106 ± 5

105 ± 7

106 ± 7

Iron (µg/dL)

66 ± 47

65 ± 49

151 ± 38

146 ± 49

Total bilirubin (mg/dL)

0.3 ± 0.2

1.5 ± 0.9

1.7 ± 1.3

0.04*

ALT (IU/L)

11 ± 8

18 ± 41

0.02*

8 ± 4

8 ± 6

AST (IU/L)

24 ± 8

29 ± 35

0.04*

35 ± 11

38 ± 20

< 0.001*

ALP (IU/L)

304 ± 160

315 ± 190

337 ± 208

328 ± 181

LDH (IU/L)

443 ± 133

452 ± 136

804 ± 353

848 ± 336

CK (IU/L)

229 ± 174

198 ± 203

312 ± 190

275 ± 121

< 0.001*

GGT (IU/L)

12 ± 7

20 ± 26

< 0.001*

96 ± 56

118 ± 77

< 0.001*

hsCRP (mg(L)

53 ± 67

59 ± 68

0.4 ± 0.8

0.2 ± 0.3

Albumin (g/dL)

3.2 ± 0.5

3.1 ± 0.3

3.8 ± 0.3

3.6 ± 0.5

< 0.001*

Protein (g/dL)

5.8 ± 0.7

5.8 ± 0.6

5.6 ± 0.6

5.3 ± 0.8

< 0.001*